反应条件
1: 90 percent / tBuOOH, D-(-)-diisopropyl tartrate, Ti(OiPr)4 2: 63 percent / DIBAL / toluene; hexane / 1.) -78 deg C, 2 h, then to 25 deg C over 1 h, 2.) reflux, 0.5 h 3: 100 percent / 1.5 percent methanolic HCl / CH2Cl2 / 0.08 h / 25 °C 4: 100 percent / pyridine, DMAP / 0.25 h / 25 °C 5: 1.) tert-butyldimethylsilyl triflate, 2.) methanolic ammonia / 1.) CH3CN, 25 deg C, 12 h, 2.) 25 deg C, 3 h View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 41 p. 5717 - 5720
