(3-苯丙基)三苯基溴化磷鎓合成路线 （共 7 条）
参考文献
Tokuyasu, Takahiro; Kunikawa, Shigeki; McCullough, Kevin J.; Masuyama, Araki; Nojima, Masatomo
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 251 - 260
反应条件
triphenylphosphine in toluene Heating / reflux;
参考文献
US2004/2504 A1, ;
Page/Page column 18 ;
US 20040002504 A1
反应条件
in tetrahydrofuran; hydrogenchloride; chloroform; acetone
反应条件
1: (3-phenylpropyl)triphenylphosphonium bromide With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-20°C; 1 h;
2: Weinreb formamide in tetrahydrofuran; hexane
T=-30 - 20°C; 4 h;
参考文献
Hisler, Kevin; Tripoli, Regis; Murphy, John A.
Tetrahedron Letters, 2006 , vol. 47, # 35 p. 6293 - 6295
反应条件
1: n-BuLi / tetrahydrofuran / 0.5 h / 20 °C
2: 3.68 g / tetrahydrofuran / 3 h / 20 °C
3: 69 percent / aq. OsO4; NMO; MeSO2NH2 / 48 h / 60 °C / pH 3
4: 67 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / 0.83 h / -78 - 20 °C
View Scheme
参考文献
Walker, Louise F.; Bourghida, Ahmed; Connolly, Stephen; Wills, Martin
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 7 p. 965 - 981
反应条件
1: (3-phenylpropyl)triphenylphosphonium bromide With sodium hydride; dimethyl sulfoxide
T=0 - 20°C;
2: pivalaldehyde in dimethyl sulfoxide
2 h;
参考文献
Tokuyasu, Takahiro; Kunikawa, Shigeki; McCullough, Kevin J.; Masuyama, Araki; Nojima, Masatomo
Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 251 - 260
反应条件
1: (3-phenylpropyl)triphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane
T=-15°C;
2: N-Methoxy-N-methyl-benzamide in tetrahydrofuran; hexane
T=-78 - 20°C; Wittig reaction;
3: With hydrogenchloride in tetrahydrofuran; diethyl ether; hexane
T=20°C;
参考文献
Murphy, John A.; Commeureuc, Aurelien G. J.; Snaddon, Thomas N.; McGuire, Thomas M.; Khan, Tanweer A.; Hisler, Kevin; Dewis, Mark L.; Carling, Robert
Organic Letters, 2005 , vol. 7, # 7 p. 1427 - 1429
