1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride in tetrahydrofuran; mineral oil T=20°C; 0.5 h; 2: benzyl 3-formylpyrrolidine-1-carboxylate in tetrahydrofuran 4 h; 3: With hydrogen; palladium hydroxide on carbon in methanol T=40°C; P=2280.15 Torr; 4 h;

1.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C 1.2: 4 h 2.1: hydrogen / Pearlman's catalist / methanol / 4 h / 40 °C View Scheme