2,2,2-三氟-1-(1-异丙基-1H-吡咯-3-基)乙酮合成路线 （共 4 条）
反应条件
potassium hydroxide in dimethyl sulfoxide
T=40°C; 20 h;
参考文献
Okada, Etsuji; Masuda, Ryoichi; Hojo, Masaru; Yoshida, Reiko
Heterocycles, 1992 , vol. 34, # 7 p. 1435 - 1441
反应条件
1: T=20°C;
2: With oxalyl dichloride; dimethyl sulfoxide
Swern Oxidation; 0.5 h;
3: With triethylamine
Swern Oxidation;
参考文献
Zanatta, Nilo; Aquino, Estefaniada C.; Da Silva, Fabio M.; Bonacorso, Helio G.; Martins, Marcos A. P.
Synthesis, 2012 , vol. 44, # 22 art. no. 961, p. 3477 - 3482,6
反应条件
1: 87 percent / trifluoroacetic acid, water / 4 h / Ambient temperature
2: 98 percent / KOH / dimethylsulfoxide / 20 h / 40 °C
View Scheme
参考文献
Okada, Etsuji; Masuda, Ryoichi; Hojo, Masaru; Yoshida, Reiko
Heterocycles, 1992 , vol. 34, # 7 p. 1435 - 1441
反应条件
in benzene
T=3°C; 4 h;
参考文献
Chadwick, Derek J.; Meakins, G. Denis; Rhodes, Caroline A.
Journal of Chemical Research, Miniprint, 1980 , # 2 p. 878 - 886
