water; lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1.5 h;

1.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: 86 percent / tetrahydrofuran; hexane / 1 h / -78 °C 2.1: 10 percent / LDA; water / tetrahydrofuran / 1.5 h / -78 °C View Scheme