4-氨基-1-[(2R,3S,4S,5R)-3,4-二羟基-5-(羟基甲基)四氢呋喃-2-基]-5-乙炔基嘧啶-2-酮合成路线 （共 3 条）
反应条件
potassium carbonate in methanol
5 h; Ambient temperature;
参考文献
Bobek; Kavai; Sharma; Grill; Dutschman; Cheng
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 2154 - 2157
反应条件
1: 80.2 percent / I2, aq. HIO3 / acetic acid; CCl4 / 4 h / 40 °C
2: 83.4 percent / Et3N, (PH3P)2PdCl2, CuI / 4 h / Ambient temperature
3: 64.6 percent / K2CO3 / methanol / 5 h / Ambient temperature
View Scheme
参考文献
Bobek; Kavai; Sharma; Grill; Dutschman; Cheng
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 2154 - 2157
反应条件
1: 83.4 percent / Et3N, (PH3P)2PdCl2, CuI / 4 h / Ambient temperature
2: 64.6 percent / K2CO3 / methanol / 5 h / Ambient temperature
View Scheme
参考文献
Bobek; Kavai; Sharma; Grill; Dutschman; Cheng
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 2154 - 2157
