4-苄基-1,3-噻唑-2-胺合成路线 （共 10 条）
反应条件
in ethanol
20 h; Heating / reflux;
参考文献
Weinstein, David S.; Gilmore, John L.; Sheppeck, James; Yang, Bingwei Vera; Kim, Soong-Hoon; Vaccaro, Wayne
Patent: US2005/187242 A1, 2005 ;
Location in patent: Page/Page column 34 ;
反应条件
thiourea in ethanol; ammonia
参考文献
Moinet; Gerard; Schaeffer; Michel; Bessin; Pierre; Bonnet; Jacqueline
Patent: US4647557 A1, 1987 ;
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane
T=80°C; 3 h;
参考文献
Yadav; Reddy, B.V. Subba; Rao, Y. Gopala; Narsaiah
Tetrahedron Letters, 2008 , vol. 49, # 15 p. 2381 - 2383
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=130°C; 0.166667 h; Microwave irradiation;
参考文献
Castagnolo, Daniele; Pagano, Mafalda; Bernardini, Martina; Botta, Maurizio
Synlett, 2009 , # 13 p. 2093 - 2096
反应条件
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / N,N-dimethyl-formamide
2: triethylamine / dichloromethane
3: lithium bromide / tetrahydrofuran; dichloromethane
4: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 130 °C / Microwave irradiation
View Scheme
参考文献
Castagnolo, Daniele; Pagano, Mafalda; Bernardini, Martina; Botta, Maurizio
Synlett, 2009 , # 13 p. 2093 - 2096
反应条件
1: triethylamine / dichloromethane
2: lithium bromide / tetrahydrofuran; dichloromethane
3: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 130 °C / Microwave irradiation
View Scheme
参考文献
Castagnolo, Daniele; Pagano, Mafalda; Bernardini, Martina; Botta, Maurizio
Synlett, 2009 , # 13 p. 2093 - 2096
反应条件
1: lithium bromide / tetrahydrofuran; dichloromethane
2: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 130 °C / Microwave irradiation
View Scheme
参考文献
Castagnolo, Daniele; Pagano, Mafalda; Bernardini, Martina; Botta, Maurizio
Synlett, 2009 , # 13 p. 2093 - 2096
参考文献
Smith et al.
Chemistry and Industry (London, United Kingdom), 1954 , p. 309
Show Details
Kaji et al.
Yakugaku Zasshi, 1955 , vol. 75, p. 438,440
Chem.Abstr., 1956 , p. 2548
Show Details
Smith; Wilson
Journal of the Chemical Society, 1955 , p. 1342,1345
反应条件
1: bromine; CS2 / anschliessend mit Thioharnstoff in H2O behandeln
2: sodium ethylate; ethanol / anschliessend mit wss. HCl erwaermen
View Scheme
参考文献
Libermann; Moyeux
Bulletin de la Societe Chimique de France, 1950 , p. 301,303
反应条件
1: etheric solution; diazomethane / anschliessendes Einleiten von HCl unter Kuehlung
View Scheme
参考文献
Kaji et al.
Yakugaku Zasshi, 1955 , vol. 75, p. 438,440
Chem.Abstr., 1956 , p. 2548
