2-(4-甲氧基苯基)-吲哚嗪合成路线 (共 8 条)
反应条件
sodium hydroxide; trichlorophosphate in N,N-dimethyl-formamide
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4614801 A1, 1986 ;
反应条件
1: in acetone
1 h; Heating;
2: With potassium carbonate
5 h;
参考文献
Chai, Wenying; Breitenbucher, J. Guy; Kwok, Annette; Li, Xiaobing; Wong, Victoria; Carruthers, Nicholas I.; Lovenberg, Timothy W.; Mazur, Curt; Wilson, Sandy J.; Axe, Frank U.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1767 - 1770
反应条件
1: acetone / 4 h / Heating
2: 22 g / K2CO3 / H2O / 8 h / 80 °C
View Scheme
参考文献
Chai, Wenying; Kwok, Annette; Wong, Victoria; Carruthers, Nicholas I.; Wu, Jiejun
Synlett, 2003 , # 13 p. 2086 - 2088
反应条件
in N,N-dimethyl-formamide
T=130°C; 0.166667 h;
参考文献
Xia, Zhiqiang; Przewloka, Teresa; Koya, Keizo; Ono, Mitsunori; Chen, Shoujun; Sun, Lijun
Tetrahedron Letters, 2006 , vol. 47, # 50 p. 8817 - 8820
反应条件
sodium hydrogencarbonate in water
0.166667 h; Heating;
参考文献
Anitha; Rajan
Journal of the Indian Chemical Society, 1989 , vol. 66, # 7 p. 460 - 462
反应条件
1: 84 percent / methanol / 0.5 h / Heating
2: 28 percent / NaHCO3 / H2O / 0.33 h / Heating
View Scheme
参考文献
Lins; Block; Doerge
Journal of Pharmaceutical Sciences, 1982 , vol. 71, # 5 p. 556 - 561
反应条件
1: 45 percent / I2 / 0.75 h / Heating
2: 52 percent / 20percent NaHCO3 / H2O / 0.17 h / Heating
View Scheme
参考文献
Anitha; Rajan
Journal of the Indian Chemical Society, 1989 , vol. 66, # 7 p. 460 - 462
反应条件
ethyl mercaptan sodium salt in N,N-dimethyl-formamide
T=100°C;
参考文献
Chai, Wenying; Breitenbucher, J. Guy; Kwok, Annette; Li, Xiaobing; Wong, Victoria; Carruthers, Nicholas I.; Lovenberg, Timothy W.; Mazur, Curt; Wilson, Sandy J.; Axe, Frank U.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1767 - 1770