4,4-二苯基-3-丁烯酸合成路线 （共 33 条）
反应条件
1: potassium tert-butylate; tert-butyl alcohol
2: aqueous hydrobromic acid; acetic acid
View Scheme
参考文献
Johnson; Petersen; Schneider
Journal of the American Chemical Society, 1947 , vol. 69, p. 74,77
反应条件
1: 90 percent / manganese(III) acetate dihydrate / acetic acid / 0.72 h / Heating
2: 25 percent / HCl / ethanol / 21 h / Heating
View Scheme
参考文献
Kurosawa, Kazu; Tsujita, Tsuyoshi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 8 p. 2391 - 2394
反应条件
1: 1.) sodium ethoxide / 1.) EtOH, 5 min. reflux, 2.) room temperature, 1,5 h
2: KOH / aq. ethanol / 6 h / Heating
3: 81 percent / acetic anhydride / 2 h / Heating
4: 0.09 g / AlCl3 / nitrobenzene / 6 h / Ambient temperature
View Scheme
参考文献
Joshi, U. R.; Khadilkar, B. M.; Samant, S. D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 75 - 76
反应条件
1: 81 percent / acetic anhydride / 2 h / Heating
2: 0.09 g / AlCl3 / nitrobenzene / 6 h / Ambient temperature
View Scheme
参考文献
Joshi, U. R.; Khadilkar, B. M.; Samant, S. D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 75 - 76
反应条件
aluminium trichloride in nitrobenzene
5 h; Ambient temperaturealso reaction in the presence of anisole;
参考文献
Joshi, U. R.; Khadilkar, B. M.; Samant, S. D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 75 - 76
反应条件
ethanol; sodium
18 h; Heating;
参考文献
Gualtieri; Teodori; Bellucci; Pesce; Piacenza
Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1621 - 1628
参考文献
Nesmejanow et al.
Doklady Akademii Nauk SSSR, 1956 , vol. 111, p. 114
Doklady Chemistry, 106-111<1956>651
反应条件
1: AlCl3
2: aqueous methanol. KOH
View Scheme
参考文献
Nesmejanow et al.
Doklady Akademii Nauk SSSR, 1956 , vol. 111, p. 114
Doklady Chemistry, 106-111<1956>651
反应条件
diethyl ether
Einleiten von Kohlendioxyd in das Reaktionsgemisch;
参考文献
Ziegler et al.
Justus Liebigs Annalen der Chemie, 1929 , vol. 473, p. 24
反应条件
anschliessend Dehydratisierung und Hydrolyse;
参考文献
Baddar et al.
Journal of the Chemical Society, 1955 , p. 461,464
Journal of the Chemical Society, 1959 , p. 1027,1030
