8,8-二甲氧基-1-氮杂螺[4.5]-2-癸酮合成路线 （共 4 条）
反应条件
1: H2 / Ra-Ni(W2) / methanol / 6 h / 20 °C / 3677.54 Torr
2: 12.8 g / NaH; MeOH / benzene / 0.5 h / 90 °C
3: aq. NaOH / methanol / 3.5 h / 100 °C
4: CSA / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Kan, Toshiyuki; Fujimoto, Teppei; Ieda, Shigeru; Asoh, Yusuke; Kitaoka, Haruka; Fukuyama, Tohru
Organic Letters, 2004 , vol. 6, # 16 p. 2729 - 2731
反应条件
camphor-10-sulfonic acid in methanol
T=20°C; 0.5 h;
参考文献
Kan, Toshiyuki; Fujimoto, Teppei; Ieda, Shigeru; Asoh, Yusuke; Kitaoka, Haruka; Fukuyama, Tohru
Organic Letters, 2004 , vol. 6, # 16 p. 2729 - 2731
反应条件
1: 12.8 g / NaH; MeOH / benzene / 0.5 h / 90 °C
2: aq. NaOH / methanol / 3.5 h / 100 °C
3: CSA / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Kan, Toshiyuki; Fujimoto, Teppei; Ieda, Shigeru; Asoh, Yusuke; Kitaoka, Haruka; Fukuyama, Tohru
Organic Letters, 2004 , vol. 6, # 16 p. 2729 - 2731
反应条件
1: aq. NaOH / methanol / 3.5 h / 100 °C
2: CSA / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Kan, Toshiyuki; Fujimoto, Teppei; Ieda, Shigeru; Asoh, Yusuke; Kitaoka, Haruka; Fukuyama, Tohru
Organic Letters, 2004 , vol. 6, # 16 p. 2729 - 2731
