perchloric acid; hydrogen; palladium on activated charcoal in acetic acid P=760 Torr; 1.) 40 deg C, 4 h, 2.) 60 deg C, 13 h;

sodium hydride in N,N-dimethyl-formamide T=60 - 70°C; 0.333333 h;

1: aq. AcOH-AcONa buffer, 10 percent aq. NaOH / ethyl acetate / 3.5 h / Ambient temperature; pH 5.2-5.3 2: 0.5 N aq. NaOH / 0.17 h / Heating 3: 1.) K2CO3 / 1.) DMF, 80 deg C, 1 h, 2.) room temperature, 3 h View Scheme

potassium carbonate 1.) DMF, 80 deg C, 1 h, 2.) room temperature, 3 h; Yield given. Multistep reaction;