反应条件
1: 3-methoxy-2-methyl-phenylamine With boron trichloride in dichloromethane; para-xylene T=0°C; 0.5 h; Inert atmosphere; 2: acetonitrile With AlCl3, aluminium chloride in dichloromethane; para-xylene T=0 - 70°C; Inert atmosphere; 3: With water in para-xylene T=70°C; 1 h;
参考文献
Kazmierski, Wieslaw M.; Hamatake, Robert; Duan, Maosheng; Wright, Lois L.; Smith, Gary K.; Jarvest, Richard L.; Ji, Jing-Jing; Cooper, Joel P.; Tallant, Matthew D.; Crosby, Renae M.; Creech, Katrina; Wang, Amy; Li, Xianfeng; Zhang, Suoming; Zhang, Yong-Kang; Liu, Yang; Ding, Charles Z.; Zhou, Yasheen; Plattner, Jacob J.; Baker, Stephen J.; Bu, Wei; Liu, Liang
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3021 - 3026