sodium hydride in tetrahydrofuran
1.) room temperature -> 0 deg C, 2.) 0 deg C -> room temperature, 2 h; Yields of byproduct given;
参考文献
Rico, Isabelle; Cantacuzene, Danielle; Wakselman, Claude
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1063 - 1066
sodium hydride in tetrahydrofuran
1.) room temperature -> 0 deg C, 2.) 0 deg C -> room temperature, 2 h; Yields of byproduct given;
参考文献
Rico, Isabelle; Cantacuzene, Danielle; Wakselman, Claude
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1063 - 1066
1: 5-methyl-1-hexyne With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: dibromo-difluoro-methane in tetrahydrofuran; hexane
T=-100 - -50°C; Further stages.;
参考文献
Xu, Bo; Mashuta, Mark S.; Hammond, Gerald B.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 43 p. 7265 - 7267
