2,2,2-三氟乙醇合成路线 （共 1089 条）
反应条件
nitric acid KineticsEquilibrium constant; Further Variations:TemperaturesPressures;
参考文献
Polish Journal of Chemistry, , vol. 80, # 9 p. 1559 - 1574
反应条件
T=57.84°C; Gas phase; Equilibrium constant;
参考文献
Chemistry - A European Journal, , vol. 15, # 18 p. 4622 - 4629
反应条件
PhotolysisUV-irradiationAir; Quantum yieldMechanism; Pressure;
参考文献
Physical Chemistry Chemical Physics, , vol. 13, # 35 p. 15936 - 15946
反应条件
sodium hydroxide; tetrabutylammomium bromide in water; chlorobenzene various conc. of NaOH/HOCH2CF3; Ea; KineticsThermodynamic data;
参考文献
Wang, Maw-Ling; Wu, Ho-Sheng
Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2344 - 2350
反应条件
(i) Na, Et2O, (ii) (NPCl2)3; Multistep reaction;
参考文献
Allcock,H.R.; Walsh,E.J.
Journal of the American Chemical Society, 1972 , vol. 94, p. 119 - 124
反应条件
water Product distributionRate constant;
参考文献
Williams, Kathleen B.; Richard, John P.
Journal of Physical Organic Chemistry, 1998 , vol. 11, # 10 p. 701 - 706
参考文献
Swamy, K.C. Kumara; Chandrasekhar; Harland, John J.; Holmes, Joan M.; Day, Roberta O.; Holmes, Robert R.
Journal of the American Chemical Society, 1990 , vol. 112, # 6 p. 2341 - 2348
反应条件
1: 2,2,2-trifluoroethanol With potassium hydroxide; Aliquatreg; 336 in dichloromethane T=30°C; 0.25 h; Inert atmosphere; 2: methyl 6-{[(methylsulfonyl)oxy]methyl}pyridine-3-carboxylate in dichloromethane 0.25 h;
参考文献
ASTRAZENECA AB; AURELL, Carl-Johan; BESIDSKI, Yevgeni; KERS, Inger; NYLOeF, Martin
Patent: WO2012/39657 A1, 2012 ;
Location in patent: Page/Page column 14 ;
WO 2012/039657 A1
反应条件
1: 2,2,2-trifluoroethanol With sodium hydride in mineral oil T=0 - 25°C; 0.5 h; Inert atmosphere; 2: 3-Bromo-2-chloro-5-nitropyridine in mineral oil 16 h; Reflux;
参考文献
F. HOFFMANN-LA ROCHE AG; GRETHER, Uwe; HEBEISEN, Paul; HOFFMANN, Torsten; ROEVER, Stephan
Patent: WO2012/49190 A1, 2012 ;
Location in patent: Page/Page column 41 ;
参考文献
Canning, Peter S. J.; Maskill, Howard; McCrudden, Katharine; Sexton, Brian
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 4 p. 789 - 800
