2,2,2-三氟乙醇合成路线 （共 1089 条）
反应条件
sodium carbonate in water T=25°C; 24 h; other buffers; percent rearrangement in different solvents; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 103, # 9 p. 2356 - 2360
反应条件
triethylamine in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Synthetic Communications, , vol. 21, # 22 p. 2391 - 2396
反应条件
boron tribromide T=-78 - 70°C; Inert atmosphereNeat (no solvent);
参考文献
Starkov, Pavel; Sheppard, Tom D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 5 p. 1320 - 1323
反应条件
n-butyllithium in diethyl ether 0°C, allowing to warm to room temp. after addn. of OHCH2CF3 and n-C4H9Li, stirring for 1 h, recooling to -78°C, addn. of BCl3, molar ratio of C6H5BCl2:OHCH2CF3:n-C4H9Li=1:3:3, stirring overnight;
参考文献
Shaw, S. Yvette; Neilson, Robert H.
Inorganic Chemistry, 1991 , vol. 30, p. 148 - 150
反应条件
in neat (no solvent) mixing (-20°C, over 15 min), stirring (room temp., 12 h); pentane addn., fractional distn.;
参考文献
Lee; Yang; Xiang; McBreen; Choi
Journal of the Electrochemical Society, 1998 , vol. 145, # 8 p. 2813 - 2818
反应条件
sodium carbonate in water T=50°C; 72 h; other solvents; Product distribution;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 21 p. 1487 - 1489
反应条件
T=130°C; 166 h; Product distribution; Further Variations:reaction time;
参考文献
Fujita, Morifumi; Mishima, Eri; Okuyama, Tadashi
Journal of Physical Organic Chemistry, 2007 , vol. 20, # 4 p. 241 - 244
反应条件
water in acetonitrile T=25°C; Kinetics; Temperature;
参考文献
Choi, Hojune; Koh, Han Joong; Ali, Dildar; Yang, Kiyull; Koo, In Sun
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 10 p. 3293 - 3297
反应条件
water T=20°C; Flash photolysis; Kinetics; Further Variations:water/trifluoroethanol ratio dependence;
参考文献
Minegishi, Shinya; Kobayashi, Shinjiro; Mayr, Herbert
Journal of the American Chemical Society, 2004 , vol. 126, # 16 p. 5174 - 5181
反应条件
water T=20°C; Kinetics; Further Variations:water/2,2,2-trifluoroethanol ratio dependence;
参考文献
Minegishi, Shinya; Kobayashi, Shinjiro; Mayr, Herbert
Journal of the American Chemical Society, 2004 , vol. 126, # 16 p. 5174 - 5181
