2,2,2-三氟乙醇合成路线 （共 1089 条）
反应条件
1: 2,2,2-trifluoroethanol With sodium hydride
T=0 - 20°C; 1.5 h; Inert atmosphere;
2: 2,5-dibromo-pyrimidine in N,N-dimethyl-formamide
T=20°C; 2 h;
参考文献
Nettekoven, Matthias; Norcross, Roger; Polara, Alessandra
Patent: US2012/108609 A1, 2012 ;
Location in patent: Page/Page column 36 ;
US 20120108609 A1
反应条件
1,4-dioxane
T=130 - 135°C;
参考文献
Purdue Res.Found.
Patent: US2452944 , 1944 ;
Full Text Show Details
Henne; Smook
Journal of the American Chemical Society, 1950 , vol. 72, p. 4380
反应条件
hydrogenchloride; water; sodium nitrite
参考文献
Wojcik-Pastuszka; Golonka; Ratajczak
Polish Journal of Chemistry, 2006 , vol. 80, # 9 p. 1559 - 1574
反应条件
2,6-dimethylpyridine in water
T=40°C; solvolysis; Mechanism;
参考文献
Hassdenteufel, Juergen Rolf; Hanack, Michael
Tetrahedron Letters, 1980 , vol. 21, p. 503 - 506
反应条件
in water
T=25°C; Rate constant;
参考文献
Toteva, Maria M.; Richard, John P.
Journal of the American Chemical Society, 1996 , vol. 118, # 46 p. 11434 - 11445
反应条件
water
T=25°C; Rate constant;
参考文献
Toteva, Maria M.; Richard, John P.
Journal of the American Chemical Society, 1996 , vol. 118, # 46 p. 11434 - 11445
反应条件
water
T=25°C; var. trifluoroethanol/water ratios, other alcohols and 1-(4-methoxyphenyl)-3-methyl-3-butyl derivatives; Rate constantProduct distributionMechanism;
参考文献
Toteva, Maria M.; Richard, John P.
Journal of the American Chemical Society, 1996 , vol. 118, # 46 p. 11434 - 11445
反应条件
water
T=25°C; Rate constant;
参考文献
Toteva, Maria M.; Richard, John P.
Journal of the American Chemical Society, 1996 , vol. 118, # 46 p. 11434 - 11445
反应条件
pyridine; thionyl chloride
1.) 0 deg C, 3 h, 2.) 25 deg C, 2 days;
参考文献
Krespan, Carl G.; Smart, Bruce E.
Journal of Organic Chemistry, 1986 , vol. 51, # 3 p. 320 - 326
反应条件
sodium carbonate
T=50°C; 144 h; Further byproducts given;
参考文献
Collins, Clair J.; Hanack, Michael; Stutz, Herbert; Auchter, Gerhard; Schoberth, Winfried
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5260 - 5268
