2-{2-[2-(2-羟基乙氧基)乙氧基]乙基}-1H-异吲哚-1,3(2H)-二酮合成路线 (共 13 条)
反应条件
1: 52 percent / pyridine / CH2Cl2 / 2.5 h / 0 - 20 °C
2: 57 percent / 1,8-diazabicyclo[5.4.0]undec-7-en / dimethylformamide / 18 h / 80 °C
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参考文献
Ossipov, Dimitri; Zamaratski, Edouard; Chattopadhyava, Jyoti
Helvetica Chimica Acta, 1999 , vol. 82, # 12 p. 2186 - 2200
反应条件
jones reagent in acetone
1 h;
参考文献
Dolle, Frederic; Hinnen, Francoise; Valette, Heric; Fuseau, Chantal; Duval, Raphael; Peglion, Jean-Louis; Crouzel, Christian
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 749 - 764
反应条件
1: hydrazine / ethanol / Inert atmosphere
2: sodium hydrogencarbonate / water / Inert atmosphere
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参考文献
Jalisatgi, Satish S.; Kulkarni, Vikas S.; Tang, Betty; Houston, Zachary H.; Lee, Mark W.; Hawthorne, M. Frederick
Journal of the American Chemical Society, 2011 , vol. 133, # 32 p. 12382 - 12385