3,5-二甲基-1-(4-苯基-1,3-噻唑-2-基)吡唑合成路线 （共 8 条）
反应条件
sodium carbonate in neat (no solvent, solid phase)
T=20°C; Hantzsch Thiazole Synthesis; 0.0833333 h; Green chemistry;
参考文献
Aggarwal, Ranjana; Kumar, Sunil; Singh, Shiv P.
Journal of Sulfur Chemistry, 2012 , vol. 33, # 5 p. 521 - 525,5
反应条件
sodium carbonate in neat (no solvent, solid phase)
T=20°C; Hantzsch Thiazole Synthesis; 0.0833333 h; Green chemistry;
参考文献
Aggarwal, Ranjana; Kumar, Sunil; Singh, Shiv P.
Journal of Sulfur Chemistry, 2012 , vol. 33, # 5 p. 521 - 525,5
反应条件
acetic acid in ethanol
1) reflux, 2) RT;
参考文献
Singh, S. P.; Kodali, Dharma R.; Dhindsa, G. S.; Sawhney, S. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 1 p. 30 - 33
反应条件
hydrogenchloride in ethanol
Hantzsch thiazole synthesis; Reflux;
参考文献
Nalajam, Guravaiah; Vedula, Rajeswar Rao
Journal of Chemical Research, 2008 , # 4 p. 195 - 197
反应条件
in ethanol
T=50 - 60°C; 3 h;
参考文献
Novikova, A. P.; Postovskii, I. Ya.; Puchkova, S. M.; Chechulina, L. A.; Tuzhilkova, T. N.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 6 p. 383 - 386
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 6 p. 46 - 49
反应条件
1: hydrogenchloride / water
2: sodium carbonate / ethanol / 3 h / |Reflux
View Scheme
参考文献
Aggarwal, Ranjana; Kumar, Sunil; Sharma, Chetan; Aneja, Kamal R.; Singh, Shiv P.
Indian Journal of Heterocyclic Chemistry, 2012 , vol. 21, # 4 p. 331 - 336
反应条件
in ethanol
T=20°C; Hantzsch thiazole synthesis; 0.25 h;
参考文献
Prakash, Richa; Kumar, Ajay; Aggarwal, Ranjana; Prakash, Om; Singh
Synthetic Communications, 2007 , vol. 37, # 15 p. 2501 - 2505
反应条件
in ethanol
6 h; Heating;
参考文献
Singh, S. P.; Sehgal, Subhash; Singh, Lukhvinder; Dhawan, S. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 154 - 155
