2-溴-5-甲氧基苯甲醛合成路线 （共 53 条）
反应条件
bromine in acetic acid T=25°C; Inert atmosphere;
参考文献
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK; SNYDER, Scott Alan; SHERWOOD, Trevor C.; ROSS, Audrey G.; OH, Hyunju; GHOSH, Sankar
Patent: WO2011/103442 A2, 2011 ;
Location in patent: Page/Page column 62-63 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 60 h;
参考文献
Bristol-Myers Squibb Company
Patent: US2008/194535 A1, 2008 ;
Location in patent: Page/Page column 30 ;
US 20080194535 A1
反应条件
pyridinium chlorochromate in dichloromethane T=20°C;
参考文献
Barbasiewicz, Michal; Blocki, Krzysztof; Malinska, Maura; Pawlowski, Robert
Dalton Transactions, 2013 , vol. 42, # 2 p. 355 - 358
反应条件
diiodine pentaoxide; potassium bromide in water T=20°C; 23 h; regioselective reaction;
参考文献
Synthetic Communications, , vol. 44, # 2 p. 181 - 187
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran; diethyl ether 1 h; Heating; 2: With pyridinium chlorochromate in dichloromethane 1 h; Heating; Further stages.;
参考文献
Spring, David R.; Krishnan, Shyam; Blackwell, Helen E.; Schreiber, Stuart L.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1354 - 1363
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; acetic acid Sommelet reaction; 2 h; RefluxInert atmosphere;
参考文献
Malashikhin, Sergey A.; Baldridge, Kim K.; Finney, Nathaniel S.
Organic Letters, 2010 , vol. 12, # 5 p. 940 - 943
反应条件
1: 86 percent / N-bromosuccinimide; AIBN / benzene / 1 h / Heating 2: dimethylformamide / 8 h / 80 °C 3: 8.7 g / aq. LiOH / tetrahydrofuran / 8 h / 23 °C 4: 96 percent / DMSO; (COCl)2; Et3N / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 29 p. 10124 - 10125
反应条件
4-hydroxy-TEMPO benzoate; sodium bromide in dichloromethane T=40°C; electrolysis;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 3 p. 796 - 800
反应条件
1: 57 percent / bromine; acetic acid 2: 95 percent / potassium carbonate View Scheme
参考文献
Organic letters, , vol. 4, # 16 p. 2711 - 2714
