4-[3,6-二氢-6-羟基-5-[4-甲基-6-(2,6,6-三甲基-1-环己烯-1-基)-3-己烯基]-2H-吡喃-2-基]-5-羟基-2(5H)-呋喃酮合成路线 （共 40 条）
反应条件
in benzene T=0°C; 3 h; Irradiation;
参考文献
Bury, Paul; Hareau, Georges; Kocienski, Philip; Dhanak, Dashyant
Tetrahedron, 1994 , vol. 50, # 29 p. 8793 - 8808
反应条件
1: 90 percent / diethyl ether 3: 94 percent / iPr2NEt / Pd(PPh3)4 / tetrahydrofuran; methanol / 24 h / 60 °C / 1520 Torr 4: 94 percent / DIBAL-H / CH2Cl2 / -80 °C 5: 60 percent / O2, rose bengal / methanol / -80 °C / Irradiation View Scheme
参考文献
Chemical Communications, , # 12 p. 1139 - 1140
反应条件
2: 94 percent / iPr2NEt / Pd(PPh3)4 / tetrahydrofuran; methanol / 24 h / 60 °C / 1520 Torr 3: 94 percent / DIBAL-H / CH2Cl2 / -80 °C 4: 60 percent / O2, rose bengal / methanol / -80 °C / Irradiation View Scheme
参考文献
Chemical Communications, , # 12 p. 1139 - 1140
反应条件
1: 94 percent / iPr2NEt / Pd(PPh3)4 / tetrahydrofuran; methanol / 24 h / 60 °C / 1520 Torr 2: 94 percent / DIBAL-H / CH2Cl2 / -80 °C 3: 60 percent / O2, rose bengal / methanol / -80 °C / Irradiation View Scheme
参考文献
Chemical Communications, , # 12 p. 1139 - 1140
反应条件
acetic acid in tetrahydrofuran 7 h; Ambient temperature;
参考文献
Katsumura, Shigeo; Fujiwara, Shinya; Isoe, Sachihiko
Tetrahedron Letters, 1985 , vol. 26, # 47 p. 5827 - 5830
反应条件
trifluoroacetic acid in dichloromethane T=0°C; 1 h;
参考文献
Synthesis, , # 9 p. 1367 - 1371
反应条件
1: 94 percent / DIBAL-H / CH2Cl2 / -80 °C 2: 60 percent / O2, rose bengal / methanol / -80 °C / Irradiation View Scheme
参考文献
Chemical Communications, , # 12 p. 1139 - 1140
反应条件
1: lithium aluminium hydride 2: PBr3 / pyridine 4: 2N HCl / 0.05 h / 0 °C 6: 95 percent / diisobutylaluminium hydride / CH2Cl2 7: DMAP, Et3N / CH2Cl2 / 0.5 h / 0 °C 8: LiCl / dimethylformamide / 0.5 h / 0 °C 10: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 11: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 12: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: PBr3 / pyridine 3: 2N HCl / 0.05 h / 0 °C 5: 95 percent / diisobutylaluminium hydride / CH2Cl2 6: DMAP, Et3N / CH2Cl2 / 0.5 h / 0 °C 7: LiCl / dimethylformamide / 0.5 h / 0 °C 9: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 10: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 11: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
2: 2N HCl / 0.05 h / 0 °C 4: 95 percent / diisobutylaluminium hydride / CH2Cl2 5: DMAP, Et3N / CH2Cl2 / 0.5 h / 0 °C 6: LiCl / dimethylformamide / 0.5 h / 0 °C 8: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 9: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 10: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
