4-[3,6-二氢-6-羟基-5-[4-甲基-6-(2,6,6-三甲基-1-环己烯-1-基)-3-己烯基]-2H-吡喃-2-基]-5-羟基-2(5H)-呋喃酮合成路线 （共 40 条）
反应条件
1: 1.) BuLi / 1.) THF, -78 deg C, 15 min 2: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 3: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 4: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: barium permanganate / CH2Cl2 / 16 h 3: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 4: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 5: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: 1.) n-BuLi / 1.) THF, -78 deg C, 1h, then 0 deg C, 2h, 2.) 0 deg C, 18h 2: Raney Ni / ethanol / 16 h 3: barium permanganate / CH2Cl2 / 16 h 5: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 6: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 7: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: Raney Ni / ethanol / 16 h 2: barium permanganate / CH2Cl2 / 16 h 4: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 5: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 6: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: O2, rose bengal / CH2Cl2; methanol / -78 °C / Irradiation 2: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 3: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: 2N hydrochloric acid / tetrahydrofuran / 2 h / Ambient temperature 2: Irradiation View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 47 p. 5827 - 5830
反应条件
1: LiBr, ZnBr2, PBr3 / tetrahydrofuran / 5 h / -60 °C 2: LDA, DMPU / tetrahydrofuran / 1.) -78 deg C, 10 min, 2.) -78 deg C, 5 h 3: AcOH, NaOAc, H2O / diethyl ether / 1 h 4: 100 percent / Et3N / benzene / 0.5 h / 0 °C 5: Me3Al/AlCl3 / benzene; tetrahydrofuran; toluene / 2 h / Ambient temperature 6: H2O, SiO2 7: 55 percent / benzene / 0 °C / Irradiation 8: TFA / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Synthesis, , # 9 p. 1367 - 1371
反应条件
1: Me3Al/AlCl3 / benzene; tetrahydrofuran; toluene / 2 h / Ambient temperature 2: H2O, SiO2 3: 55 percent / benzene / 0 °C / Irradiation 4: TFA / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Synthesis, , # 9 p. 1367 - 1371
反应条件
1: Me3Al/AlCl3 / benzene; tetrahydrofuran; toluene / 2 h / Ambient temperature 2: H2O, SiO2 3: 55 percent / benzene / 0 °C / Irradiation 4: TFA / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Synthesis, , # 9 p. 1367 - 1371
反应条件
1: 55 percent / benzene / 0 °C / Irradiation 2: TFA / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Synthesis, , # 9 p. 1367 - 1371
