4-碘-1-甲基-1H-吡唑-5-羧酸甲酯合成路线 （共 3 条）
反应条件
sulfuric acid; iodine; iodic acid in tetrachloromethane; acetic acid T=80°C; 0.5 h;
参考文献
Vasilevskii, S. F.; Shvartsberg, M. S.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, # 5 p. 778 - 784
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 5 p. 1071 - 1077
反应条件
1: 99.7 percent / CuI, Pd(PPh)3Cl2 / diethylamine / 25 h / 50 °C
2: 1.) KOH, m-pentaphenyl ether, 2.) aq. KOH / 1.) 110 - 130 deg C, 1 mm Hg, 2.) 20 deg C, 48 h
3: 62.5 percent / PhCCCu / pyridine / Heating
View Scheme
参考文献
Shvartsberg, M. S.; Vasilevskii, S. F.; Anisimova, T. V.; Gerasimov, V. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 6 p. 1071 - 1076
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 6 p. 1342 - 1348
反应条件
1: 99.7 percent / CuI, Pd(PPh)3Cl2 / diethylamine / 25 h / 50 °C
2: 1.) KOH, m-pentaphenyl ether, 2.) aq. KOH / 1.) 110 - 130 deg C, 1 mm Hg, 2.) 20 deg C, 48 h
View Scheme
参考文献
Shvartsberg, M. S.; Vasilevskii, S. F.; Anisimova, T. V.; Gerasimov, V. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 6 p. 1071 - 1076
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 6 p. 1342 - 1348
