1-(4-氟苯基)-1,4-二氮杂环庚烷合成路线 （共 2 条）
反应条件
1: With hydrogenchloride in 1,4-dioxane; methanol
T=20°C; 1 h;
2: With potassium carbonate in water
参考文献
Saito, Keiji; Nakao, Akira; Shinozuka, Tsuyoshi; Shimada, Kousei; Matsui, Satoshi; Oizumi, Kiyoshi; Yano, Kazuki; Ohata, Keiko; Nakai, Daisuke; Nagai, Yoko; Naito, Satoru
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1628 - 1642
反应条件
1: copper(l) iodide; potassium phosphate / isopropyl alcohol / 10 h / 80 °C / |Inert atmosphere
2: hydrogenchloride / 1,4-dioxane; methanol / 1 h / 20 °C
View Scheme
参考文献
Saito, Keiji; Nakao, Akira; Shinozuka, Tsuyoshi; Shimada, Kousei; Matsui, Satoshi; Oizumi, Kiyoshi; Yano, Kazuki; Ohata, Keiko; Nakai, Daisuke; Nagai, Yoko; Naito, Satoru
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1628 - 1642
