(E)-4-苯基-3-丁烯胺合成路线 （共 11 条）
反应条件
(i) aq. HClO4, (ii) NaNO2; Multistep reaction;
参考文献
Hanack,M. et al.
Justus Liebigs Annalen der Chemie, 1965 , vol. 690, p. 98 - 114
反应条件
hydrogenchloride; indium in tetrahydrofuran
T=20°C; 3 h;
参考文献
Lee, Jung Gyu; Choi, Kyung Il; Koh, Hun Yeong; Kim, Youseung; Kang, Yonghan; Cho, Yong Seo
Synthesis, 2001 , # 1 p. 81 - 84
反应条件
lithium aluminium tetrahydride in diethyl ether
3 h; Ambient temperature;
参考文献
Imada, Yasushi; Shibata, Ou; Murahashi, Shun-Ichi
Journal of Organometallic Chemistry, 1993 , vol. 451, # 1.2 p. 183 - 194
反应条件
n-butyllithium in tetrahydrofuran
15 h;
参考文献
Maryanoff,B.E.; Reitz,A.; Duhl-Emswiler,B.
Journal of the American Chemical Society, 1985 , vol. 10, p. 217
反应条件
hydrazine hydrate in ethanol
T=20°C; 10 h; optical yield given as percent de;
参考文献
Gerpe, Alejandra; Bollini, Mariela; Gonzalez, Mercedes; Cerecetto, Hugo
Synthetic Communications, 2009 , vol. 39, # 1 p. 29 - 47
反应条件
1: With water; methylamine in ethanol
T=20°C; 48 h;
2: With hydrogenchloride; water
T=20°C; 2 h; optical yield given as percent de;
参考文献
Gerpe, Alejandra; Bollini, Mariela; Gonzalez, Mercedes; Cerecetto, Hugo
Synthetic Communications, 2009 , vol. 39, # 1 p. 29 - 47
反应条件
1: 72 percent / NH4Cl, Rh6(CO)16, Et3N, 4-N,N-dimethylaminopyridine (DMAP) / dimethylsulfoxide / 6 h / 50 °C / 15200 Torr
2: 71 percent / LiAlH4 / diethyl ether / 3 h / Ambient temperature
View Scheme
参考文献
Imada, Yasushi; Shibata, Ou; Murahashi, Shun-Ichi
Journal of Organometallic Chemistry, 1993 , vol. 451, # 1.2 p. 183 - 194
反应条件
n-butyllithium in tetrahydrofuran
Title compound not separated from byproducts;
参考文献
Maryanoff, Bruce E.; Duhl-Emswiler, B. A.; Reitz, Allen B.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 18, p. 187 - 190
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Kotschetkow; Dudykina
Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 2399,2401; engl. Ausg. S. 2437, 2439
反应条件
1: NaOH; methanol
2: LiAlH4; diethyl ether
View Scheme
参考文献
Kotschetkow; Dudykina
Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 2399,2401; engl. Ausg. S. 2437, 2439
