反应条件
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C 2: [bis(acetoxy)iodo]benzene; palladium diacetate; acetic acid / toluene / 24 h / 110 °C / Inert atmosphere 3: hydrogenchloride; water / 1,4-dioxane / 24 h / 20 °C 4: sodium hydrogencarbonate / 1,4-dioxane / 3 h / 20 °C 5: 10 palladium on activated charcoal; hydrogen / ethyl acetate / 14 h / 20 °C / 760.05 Torr 6: lithium hydroxide hydrate / tetrahydrofuran; methanol; water / 14 h / 20 °C View Scheme
参考文献
He, Gang; Zhao, Yingsheng; Zhang, Shuyu; Lu, Chengxi; Chen, Gong
Journal of the American Chemical Society, 2012 , vol. 134, # 1 p. 3 - 6
