(3R,4R)-1-苄基-3,4-二羟基吡咯烷-2,5-二酮合成路线 （共 11 条）
反应条件
1: 1.) BF3*Et2O, NaBH4, 2.) NaF, 6 N HCl / 1.) diglycol dimethyl ether, 2 h, 70 deg C, 2.) diglycol dimethyl ether, 30 min, 100 deg C
2: 87 percent / triethylamine / CH2Cl2 / 0.5 h / Ambient temperature
3: dimethylformamide / -15 °C
View Scheme
参考文献
Nagel, Ulrich; Kinzel, Elke; Andrade, Juan; Prescher, Guenter
Chemische Berichte, 1986 , vol. 119, # 11 p. 3326 - 3343
