N-叔丁氧羰基-1,3-丙二胺合成路线 （共 26 条）
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=0 - 20°C; 4 h;
参考文献
Kurtan; Nesnas; Li; Huang; Nakanishi; Berova
Journal of the American Chemical Society, 2001 , vol. 123, # 25 p. 5962 - 5973
反应条件
triethylamine; potassium iodide in dichloromethane T=40°C; 50 h;
参考文献
Shibata; Biplab Kumar Das; Honjo; Takeuchi
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 14 p. 1605 - 1611
反应条件
tetrabutylammomium bromide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in acetonitrile T=20°C; 0.0833333 h; Inert atmosphereMolecular sieve;
参考文献
Drouet, Fleur; Fontaine, Patrice; Masson, Geraldine; Zhu, Jieping
Synthesis, 2009 , # 8 art. no. T19708SS, p. 1370 - 1374
反应条件
1: 72 percent / methanol / Ambient temperature
2: 98 percent / H2, NaOH / Raney nickel / ethanol; H2O / 3 h / 760 Torr / Ambient temperature; pH 10
View Scheme
参考文献
Arasujo, M. Joso S. M. P.; Ragnarsson, Ulf; Trigo, M. Joaquina S. A. Amaral; Almeida, M. Lurdes S.
Journal of Chemical Research, Miniprint, 1996 , # 8 p. 2143 - 2161
反应条件
1: 57 percent / K2CO3 / acetonitrile / 24 h / 60 °C
2: 100 percent / Et3N / methanol / 20 °C
3: 64 percent / NH4OH; NH3; H2 / Raney nickel / ethanol / 24 h / 1810.07 Torr
View Scheme
参考文献
Corce, Vincent; Morin, Emmanuelle; Guiheneuf, Solene; Renault, Eric; Renaud, Stephanie; Cannie, Isabelle; Tripier, Raphael; Lima, Luis M. P.; Julienne, Karine; Gouin, Sebastien G.; Loreal, Olivier; Deniaud, David; Gaboriau, Francois
Bioconjugate Chemistry, 2012 , vol. 23, # 9 p. 1952 - 1968
参考文献
Sumitomo Pharmaceuticals Company, Limited
Patent: EP1300401 A1, 2003 ;
