5,6-二氨基-1-乙基-3-丙基嘧啶-2,4(1h,3h)-二酮合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol
P=1551.49 Torr; 2 h;
参考文献
Zeng, Dewan; Belardinelli, Luiz
Patent: US2006/58322 A1, 2006 ;
Location in patent: Page/Page column 17 ;
US 20060058322 A1
反应条件
1: dichloromethane; aqueous ammonia; methanol
2: sodium nitrite; acetic acid / water
3: palladium / methanol
View Scheme
参考文献
Gilead Sciences, Inc.
Patent: US2012/3329 A1, 2012 ;
US 20120003329 A1
反应条件
1: N,N-dimethyl acetamide
2: potassium carbonate / N-methyl-acetamide
3: dichloromethane; aqueous ammonia; methanol
4: sodium nitrite; acetic acid / water
5: palladium / methanol
View Scheme
参考文献
Gilead Sciences, Inc.
Patent: US2012/3329 A1, 2012 ;
US 20120003329 A1
反应条件
1: potassium carbonate / N-methyl-acetamide
2: dichloromethane; aqueous ammonia; methanol
3: sodium nitrite; acetic acid / water
4: palladium / methanol
View Scheme
参考文献
Gilead Sciences, Inc.
Patent: US2012/3329 A1, 2012 ;
US 20120003329 A1
