potassium hydroxide in dichloromethane T=20°C; 1 h;

hydrogen; palladium on activated carbon in ethanol; acetic acid T=20°C; 15 h;

1: 1,3-dihydro-indol-2-one With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 0.5 h; 2: N-(2,2'-bischloro)diethyl-N-(1,1-dimethylethoxy)carbonyl amine in tetrahydrofuran T=-78 - 20°C; 21 h;