3-羟基-5-[(1-甲基乙基)氧基]-N-1,3-噻唑-2-基苯甲酰胺合成路线 (共 2 条)
反应条件
1: With DMEG; triethylamine in chloroform
T=0 - 20°C; 13 h;
2: With ammonium chloride in chloroform; water
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1600442 A1, 2005 ;
Location in patent: Page/Page column 78 ;
反应条件
methyl-phenyl-thioether; trifluoroacetic acid
T=18 - 25°C; 18 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/80360 A1, 2005 ;
Location in patent: Page/Page column 76 ;
WO 2005/080360 A1