L-苯丙氨酸甲酯盐酸盐合成路线 （共 169 条）
反应条件
anion exchange resin in dichloromethane 0.0833333 h;
参考文献
Bhaskara Redddy; Kumari, Y. Bharathi; Ananda, Kuppanna
International Journal of Peptide Research and Therapeutics, 2013 , vol. 19, # 3 p. 225 - 229
反应条件
hydrogen; triethylamine; palladium dichloride in ethylene glycol dimethyl ether T=20°C; P=912 Torr; stereoselectivity; MechanismRate constant;
参考文献
Lyubeznova, M. R.; Karpeiskaya, E. I.; Klabunovskii, E. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 4.1 p. 720 - 726
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 4 p. 811 - 818
反应条件
water; triethylamine in ethylene glycol dimethyl ether Yield given. Yields of byproduct given;
参考文献
Lyubeznova, M. R.; Karpeiskaya, E. I.; Klabunovskii, E. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 4.1 p. 720 - 726
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 4 p. 811 - 818
反应条件
hydrogen; triethylamine in ethylene glycol dimethyl ether stereoselectivity; other solvents, other amino esters;
参考文献
Lyubeznova, M. R.; Karpeiskaya, E. I.; Klabunovskii, E. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 4.1 p. 720 - 726
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 4 p. 811 - 818
反应条件
ammonia in methanol 96 h; Ambient temperature;
参考文献
Brutsche, Andreas; Hartke, Klaus
Liebigs Annalen der Chemie, 1992 , # 9 p. 921 - 926
反应条件
1: NaHCO3 / H2O; tetrahydrofuran / Ambient temperature 2: diisobutylaluminium hydride / toluene; hexane / -77 °C 3: sodium metabisulfite / H2O / 5 h / Ambient temperature 4: 25percent aq. HCl / 12 h / 80 °C 5: 10N NaOH, Na2CO3 / H2O; tetrahydrofuran / Ambient temperature 6: KHCO3 / dimethylformamide / 12 h 7: aq. LiOH / methanol; tetrahydrofuran View Scheme
参考文献
Yuan; Munoz; Wong; Haeggstrom; Wetterholm; Samuelsson
Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 211 - 220
反应条件
1: With triethylamine in methanol; diethyl ether T=-10°C; 2 h; 2: With ammonia in methanol 48 h;
参考文献
Laurent, Sophie; Botteman, Francois; Vander Elst, Luce; Muller, Robert N.
Helvetica Chimica Acta, 2004 , vol. 87, # 5 p. 1077 - 1089
反应条件
hydrazine hydrate in methanol T=20°C; 24 h;
参考文献
Kudelko, Agnieszka; Zielinski, Wojciech; Jasiak, Karolina
Tetrahedron Letters, 2013 , vol. 54, # 35 p. 4637 - 4640
反应条件
in ethanol; water T=20°C; 24 h;
参考文献
Da Costa, Cristiane F.; Pinheiro, Alessandra C.; De Almeida, Mauro V.; Lourenco, Maria C.S.; De Souza, Marcus V.N.
Chemical Biology and Drug Design, 2012 , vol. 79, # 2 p. 216 - 222
反应条件
1: 40.6 g / DCC, NEt3 / CH2Cl2 / Ambient temperature 2: H2SO4, H2O / 2 h / 80 - 85 °C 3: 65 percent / K2CO3 / tetrahydrofuran; H2O / 2 h / Ambient temperature View Scheme
参考文献
Sawayama; Itokawa; Shimada; Doi; Kimura; Nishim ura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 2 p. 529 - 531
