L-苯丙氨酸甲酯盐酸盐合成路线 （共 169 条）
反应条件
1: 100 percent / Et3N / CH2Cl2 / 24 h / Ambient temperature 2: diisobutylaluminium hydride / hexane; CH2Cl2 / 0.1 h / -78 °C View Scheme
参考文献
Van den Broek; Fennis; Arevalo; Lazaro; Ballesta; Lelieveld; Ottenheijm
European Journal of Medicinal Chemistry, 1989 , vol. 24, # 5 p. 503 - 510
反应条件
1: Et3N 2: aq. NaOH View Scheme
参考文献
Krainova,B.L. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1969 , vol. 39, # 1 p. 92 - 96,81 - 83
反应条件
1: triethylamine / dichloromethane / 0 - 25 °C 2: lithium borohydride / tetrahydrofuran / 0 - 20 °C 3: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere View Scheme
参考文献
Manna, Sudipta Kumar; Panda, Gautam
RSC Advances, 2013 , vol. 3, # 40 p. 18332 - 18338
反应条件
triethylamine in dichloromethane 24 h; Ambient temperature;
参考文献
Sturrock, Edward; Nchinda, Aloysius; Chibale, Kelly
Patent: US2009/281160 A1, 2009 ;
Location in patent: Page/Page column 9 ;
反应条件
sodium chloride; sodium carbonate in methanol; water; ethyl acetate
参考文献
Onishi, Tomoyuki; Otake, Yasuyuki; Nakazawa, Masakazu; Izawa, Kunisuke
Patent: US2002/35296 A1, 2002 ;
反应条件
in ethylene glycol dimethyl ether T=20°C;
参考文献
Ouchi, Hidekazu; Saito, Yukako; Yamamoto, Yutaka; Takahata, Hiroki
Organic Letters, 2002 , vol. 4, # 4 p. 585 - 587
Title/Abstract Full Text View citing articles Show Details
Saito, Yukako; Ouchi, Hidekazu; Takahata, Hiroki
Tetrahedron, 2006 , vol. 62, # 50 p. 11599 - 11607
反应条件
sodium carbonate in water; ethyl acetate T=0 - 16°C;
参考文献
Sun, Dequn; Zhang, Lingzi; Wang, Jin
Asian Journal of Chemistry, 2012 , vol. 24, # 1 p. 319 - 322
反应条件
1: 98 percent / aq. NaHCO3 / dioxane / 12 h / 20 °C 2: 80 percent / DIBAL-H / CH2Cl2; hexane / 2 h / -78 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 36 p. 7877 - 7883
反应条件
1: NaHCO3 2: LiBH4 View Scheme
参考文献
Krasinski, Antoni; Gruza, Henryk; Jurczak, Janusz
Heterocycles, 2001 , vol. 54, # 2 p. 581 - 584
反应条件
1: NaHCO3 2: LiBH4 3: NaHCO3; NaOCl; NaBr / TEMPO / ethyl acetate; toluene; H2O / -5 °C View Scheme
参考文献
Krasinski, Antoni; Gruza, Henryk; Jurczak, Janusz
Heterocycles, 2001 , vol. 54, # 2 p. 581 - 584
