4-[2-[2-(3,4-二甲氧基苯基)乙基氨基]-1-羟基乙基]苯-1,2-二醇合成路线 （共 5 条）
参考文献
Tanabe Seiyaku Co., Ltd.
Patent: US3952021 A1, 1976 ;
US 3952021 A
反应条件
(ethylenedinitrilo)tetraacetic acid disodium salt; iron(II) chloride; ascorbic acid powder
T=37°C; 1 h; 0.1 M phosphate buffer ( pH = 6.6 ); product distribution determined by MS of O-trimethylsilyl derivatives; Product distribution;
参考文献
Suzuki; Hashimura; Takeyama
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3859 - 3867
反应条件
(ethylenedinitrilo)tetraacetic acid disodium salt; iron(II) chloride; ascorbic acid powder
T=37°C; 1 h; 0.1 M phosphate buffer ( pH = 6.6 ); product distribution determined by MS of O-trimethylsilyl derivatives; Product distribution;
参考文献
Suzuki; Hashimura; Takeyama
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3859 - 3867
反应条件
(ethylenedinitrilo)tetraacetic acid disodium salt; iron(II) chloride; ascorbic acid powder
T=37°C; 1 h; 0.1 M phosphate buffer ( pH = 6.6 ); product distribution determined by MS of O-trimethylsilyl derivatives; Product distribution;
参考文献
Suzuki; Hashimura; Takeyama
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3859 - 3867
反应条件
(ethylenedinitrilo)tetraacetic acid disodium salt; iron(II) chloride; ascorbic acid powder
T=37°C; 1 h; 0.1 M phosphate buffer ( pH = 6.6 ); product distribution determined by MS of O-trimethylsilyl derivatives; Product distribution;
参考文献
Suzuki; Hashimura; Takeyama
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3859 - 3867
