2-乙酰基-3,4-二氢-5,8-二甲氧基萘合成路线 （共 27 条）
反应条件
1: polyphosphoric acid
2: 92 percent / POCl3 / dimethylformamide / 6 h / 80 °C
4: 48 percent / pyridinium dichromate
View Scheme
参考文献
Reddy, M. Parameswara; Rao, G. S. Krishna
Tetrahedron Letters, 1981 , vol. 22, # 36 p. 3549 - 3550
反应条件
trichlorophosphate in chloroform
4 h; Heating;
参考文献
Rao, A. V. Rama; Deshpande, V. H.; Sathaye, K. M.; Jaweed, S. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 697 - 702
反应条件
1: dl-10-camphorsulfonic acid / benzene / 1.25 h / Heating
2: N-bromoacetamide / dimethylformamide; H2O / 21.5 h / 0 °C
3: 100 percent / triethylamine / methanol / 0.25 h / 0 °C
4: 57 percent / tributyltin hidride, α,α'-azobis(isobutyronitrile) / benzene / 6 h / 65 °C
5: 71 percent / concd. HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Suzuki; Kimura; Terashima
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 11 p. 3559 - 3572
反应条件
1: 100 percent / triethylamine / methanol / 0.25 h / 0 °C
2: 57 percent / tributyltin hidride, α,α'-azobis(isobutyronitrile) / benzene / 6 h / 65 °C
3: 71 percent / concd. HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Suzuki; Kimura; Terashima
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 11 p. 3559 - 3572
反应条件
1: N-bromoacetamide / dimethylformamide; H2O / 21.5 h / 0 °C
2: 100 percent / triethylamine / methanol / 0.25 h / 0 °C
3: 57 percent / tributyltin hidride, α,α'-azobis(isobutyronitrile) / benzene / 6 h / 65 °C
4: 71 percent / concd. HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Suzuki; Kimura; Terashima
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 11 p. 3559 - 3572
反应条件
1: 57 percent / tributyltin hidride, α,α'-azobis(isobutyronitrile) / benzene / 6 h / 65 °C
2: 71 percent / concd. HCl / ethanol / 2 h / Heating
View Scheme
参考文献
Suzuki; Kimura; Terashima
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 11 p. 3559 - 3572
反应条件
1: 58 percent / 1.) NaOH / H2O / 1 h / Ambient temperature
2: 82 percent / AlCl3 / CH2Cl2 / -5 °C
3: 94 percent / 1.) aq. NaOH / methanol / 12 h / Heating
View Scheme
参考文献
Russell; Collin; Crane; et al.
Australian Journal of Chemistry, 1984 , vol. 37, # 8 p. 1721 - 1728
反应条件
1: 79 percent / tetrahydrofuran / 18 h / Ambient temperature
2: 61 percent / 80percent formic acid / 2 h / 100 - 110 °C
View Scheme
参考文献
Tanno; Terashima
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 811 - 820
反应条件
1: Et3N; PhNCO / 1,2-dichloro-ethane / 12 h
2: H2; H3BO3; Raney-Ni / methanol; H2O
3: MsCl; Et3N; DMAP
View Scheme
参考文献
Chavan, Subhash P.; Subbarao, Y. Tripura; Gopal, Chittiboyina Amar
Journal of Chemical Research - Part S, 1999 , # 6 p. 380 - 381
反应条件
1: H2; H3BO3; Raney-Ni / methanol; H2O
2: MsCl; Et3N; DMAP
View Scheme
参考文献
Chavan, Subhash P.; Subbarao, Y. Tripura; Gopal, Chittiboyina Amar
Journal of Chemical Research - Part S, 1999 , # 6 p. 380 - 381
