(S)-2-(苄氧羰氨基)-3-丁烯酸甲酯合成路线 (共 48 条)
反应条件
1: 98 percent 2: 90 percent / sodium methoxide / methanol / 2 h / 0 °C 3: 60 percent / lead tetraacetate, cupric acetate monohydrate / benzene / 15 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 14 p. 1425 - 1428
反应条件
1: 90 percent / sodium methoxide / methanol / 2 h / 0 °C 2: 60 percent / lead tetraacetate, cupric acetate monohydrate / benzene / 15 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 25, # 14 p. 1425 - 1428
反应条件
phosphorous acid trimethyl ester in xylene 24 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 36, # 3 p. 893 - 901
反应条件
in 1,3,5-trimethyl-benzene 24 h; Heating;
参考文献
Hartley, David M.; Coward, James K.
Journal of Organic Chemistry, 2005 , vol. 70, # 17 p. 6757 - 6774
反应条件
1: 100 percent / diethyl ether 2: 100 percent / NaIO4 / methanol; H2O / 2 h / 0 °C 3: 72 percent / xylene / 36 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 9 p. 1149 - 1158
反应条件
in methanol; hexane; benzene Yield given. Yields of byproduct given;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 43, # 3 p. 398 - 402
反应条件
1: dioxane / 85 °C 2: H2O2; NaOH View Scheme
参考文献
Krebs, Andreas; Ludwig, Verena; Pfizer, Jose; Duerner, Gerd; Goebel, Michael W.
Chemistry - A European Journal, 2004 , vol. 10, # 2 p. 544 - 553
反应条件
1: acetonitrile / 2 h / 0 - 25 °C
2: O3 / CCl4 / -20 °C
View Scheme
参考文献
Thornberry, N. A.; Bull, H. G.; Taub, D.; Greenlee, W. J.; Patchett, A. A.; Cordes, E. H.
Journal of the American Chemical Society, 1987 , vol. 109, # 24 p. 7543 - 7544