1: 55 percent / PTS / methanol / 10 h / Ambient temperature 2: 68.5 percent / pyridinium chlorochromate, sodium acetate / CH2Cl2 / 2 h 3: 1) sodium hydride / 1) diglyme, 2) THF, a) room temperature, 8 h, b) 50 deg C, 1.5 h, c) overnight 4: 78 percent / 10percent aq. methanolic KOH / methanol / 2 h / Heating 5: 72.5 percent / triethylamine, POCl5 / CH2Cl2 / 1) 0 deg C, 1 h, 2) room temperature, 30 min View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4122952', constants.ctx, '0')">sodium hydride</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '506008', constants.ctx, '0')">dimethyl sulfoxide</a> <br />&nbsp;2) THF, a) overnight, b) 50 deg C, 30 min;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;