反应条件
1: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2. -65 deg C, 1 h, 2.) CH2Cl2, -60 deg C 30 min
2: 1.) LDA / 1.) THF, hexane, -78 deg C, 10 min, 2.) THF, hexane, -78 to -20 deg C, 4 h
3: 90 percent / KOH / ethanol; H2O / Ambient temperature
4: (COCl)2 / benzene / 1 h / Heating
5: Et3N / diethyl ether / -5 - 20 °C
View Scheme
参考文献
Strunz, George M.; Finlay, Heather
Tetrahedron, 1994 , vol. 50, # 38 p. 11113 - 11122
