1: 80 percent / NIS, MS, TfOH / CH2Cl2 / 2 h / -40 °C 2: H2 / Pd / methanol / 6 h / Ambient temperature 3: dimethylformamide / 2.5 h / 80 °C 4: 95 percent / NaOMe, MeOH / 0.75 h / Ambient temperature View Scheme