1: With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.666667 h;
2: With tri-isopropoxy-borane in tetrahydrofuran; hexane
T=20°C;
3: With hydrogenchloride; water in tetrahydrofuran; hexane
T=20°C; 0.25 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2003/84917 A1, 2003 ;
Location in patent: Page/Page column 63 ;