2-(3,4-二氟苯基)-4,4,5,5-四甲基-1,3,2-二噁硼烷合成路线 （共 5 条）
反应条件
magnesium; triethylamine in tetrahydrofuran
Barbier-type reaction; 15 h; Inert atmosphereReflux;
参考文献
Pintaric, Christine; Olivero, Sandra; Gimbert, Yves; Chavant, Pierre Y.; Dunach, Elisabet
Journal of the American Chemical Society, 2010 , vol. 132, # 34 p. 11825 - 11827
反应条件
in ethanol
T=20°C; 0.5 h;
参考文献
Takagi, Jun; Yamakawa, Tetsu
Tetrahedron Letters, 2013 , vol. 54, # 2 p. 166 - 169
反应条件
tert.-butylnitrite in acetonitrile
T=80°C; 2 h;
参考文献
Qiu, Di; Jin, Liang; Zheng, Zhitong; Meng, He; Mo, Fanyang; Wang, Xi; Zhang, Yan; Wang, Jianbo
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1923 - 1933
反应条件
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / ethanol / 2 h / 80 °C / |Inert atmosphere
2: ethanol / 0.5 h / 20 °C
View Scheme
参考文献
Takagi, Jun; Yamakawa, Tetsu
Tetrahedron Letters, 2013 , vol. 54, # 2 p. 166 - 169
反应条件
1.1: palladium diacetate; potassium iodide; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; triethylamine / ethyl acetate / 16 h / 50 °C / |Inert atmosphere; |Schlenk technique
2.1: methanol / ethyl acetate / 1 h / -5 - 20 °C / |Inert atmosphere; |Schlenk technique
2.2: 4 h / 20 °C / |Inert atmosphere; |Schlenk technique
View Scheme
参考文献
Guerrand, Helene D. S.; Marciasini, Ludovic D.; Jousseaume, Melissa; Vaultier, Michel; Pucheault, Mathieu
Chemistry - A European Journal, 2014 , vol. 20, # 19 p. 5573 - 5579
