1: carbon monoxide With Cu(OAc)2*2H2O; tetrabutylammomium bromide; palladium dichloride in acetonitrile T=40°C; P=760.051 Torr; 2 h; Inert atmosphere; 2: methanol; 5-bromo-1-pentene With oxygen in acetonitrile T=60°C; 24 h; Inert atmosphere; chemoselective reaction;

in dichloromethane T=20°C; Wittig Olefination; Overall yield = 91 percent; Overall yield = 27.1 g;

sodium hydride 1) THF, r.t.; 2) -78 deg C, 15 min; Yield given. Multistep reaction;