1: 4-methoxy-benzoic acid With sodium hydrogencarbonate; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane; water
T=0°C; 0.0833333 h;
2: chloromethyl chlorosulphate in dichloromethane; water
参考文献
SEMAFORE PHARMACEUTICALS, INC.; GARLICH, Joseph, R.; DURDEN, Donald, L.
Patent: WO2004/89925 A1, 2004 ;
Location in patent: Page 43 ;
WO 2004/089925 A1