7-氯-5-(2-氯苯基)-1,5-二氢-4,1-苯并硫氮杂卓-2(3H)-酮合成路线 （共 4 条）
反应条件
1: With aluminum oxide; trifluoroacetic acid
0.116667 h; microwave irradiation;
2: With sodium carbonate in water
0.333333 h; microwave irradiation; Further stages.;
参考文献
Pei, Yazhong; Lilly, Michael J.; Owen, David J.; D'Souza, Lawrence J.; Tang, Xiao-Qing; Yu, Jinghua; Nazarbaghi, Ramina; Hunter, Andrew; Anderson, Christen M.; Glasco, Susan; Ede, Nicholas J.; James, Ian W.; Maitra, Uday; Chandrasekaran; Moos, Walter H.; Ghosh, Soumitra S.
Journal of Organic Chemistry, 2003 , vol. 68, # 1 p. 92 - 103
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine in tetrahydrofuran
T=20°C; 20 h;
参考文献
Pei, Yazhong; Lilly, Michael J.; Owen, David J.; D'Souza, Lawrence J.; Tang, Xiao-Qing; Yu, Jinghua; Nazarbaghi, Ramina; Hunter, Andrew; Anderson, Christen M.; Glasco, Susan; Ede, Nicholas J.; James, Ian W.; Maitra, Uday; Chandrasekaran; Moos, Walter H.; Ghosh, Soumitra S.
Journal of Organic Chemistry, 2003 , vol. 68, # 1 p. 92 - 103
反应条件
1: 47 percent / trifluoroacetic acid / 96 h / 20 °C
2: 100 percent / NaOH / H2O; tetrahydrofuran; methanol / 1 h / 20 °C
3: 0.462 g / diisopropylethylamine; 4-dimethylaminopyridine; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / tetrahydrofuran / 20 h / 20 °C
View Scheme
参考文献
Pei, Yazhong; Lilly, Michael J.; Owen, David J.; D'Souza, Lawrence J.; Tang, Xiao-Qing; Yu, Jinghua; Nazarbaghi, Ramina; Hunter, Andrew; Anderson, Christen M.; Glasco, Susan; Ede, Nicholas J.; James, Ian W.; Maitra, Uday; Chandrasekaran; Moos, Walter H.; Ghosh, Soumitra S.
Journal of Organic Chemistry, 2003 , vol. 68, # 1 p. 92 - 103
反应条件
1: 100 percent / NaOH / H2O; tetrahydrofuran; methanol / 1 h / 20 °C
2: 0.462 g / diisopropylethylamine; 4-dimethylaminopyridine; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / tetrahydrofuran / 20 h / 20 °C
View Scheme
参考文献
Pei, Yazhong; Lilly, Michael J.; Owen, David J.; D'Souza, Lawrence J.; Tang, Xiao-Qing; Yu, Jinghua; Nazarbaghi, Ramina; Hunter, Andrew; Anderson, Christen M.; Glasco, Susan; Ede, Nicholas J.; James, Ian W.; Maitra, Uday; Chandrasekaran; Moos, Walter H.; Ghosh, Soumitra S.
Journal of Organic Chemistry, 2003 , vol. 68, # 1 p. 92 - 103
