5-O-(叔丁基二甲基甲硅烷基)-2,3-O-异亚丙基-D-核酸γ-内酯合成路线 （共 10 条）
反应条件
1H-imidazole in N,N-dimethyl-formamide T=20°C; 16 h;
参考文献
Jones, Nigel A.; Jenkinson, Sarah F.; Soengas, Raquel; Fanefjord, Mette; Wormald, Mark R.; Dwek, Raymond A.; Kiran, Gullapalli P.; Devendar, Rao; Takata, Goro; Morimoto, Kenji; Izumori, Ken; Fleet, George W.J.
Tetrahedron Asymmetry, 2007 , vol. 18, # 6 p. 774 - 786
反应条件
molecular sieve; tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide in dichloromethane T=20°C; 0.5 h;
参考文献
Alessandrini, Laura; Casati, Silvana; Ciuffreda, Pierangela; Ottria, Roberta; Santaniello, Enzo
Journal of Carbohydrate Chemistry, 2008 , vol. 27, # 5 p. 332 - 344
反应条件
1: DMAP; Et3N / CH2Cl2 / 6 h / 0 °C 2: 4.00 g / KMnO4 / acetone / 6 h / 50 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 31 p. 6609 - 6617
反应条件
1: 58 percent / TEA, DMAP / CH2Cl2 2: 81 percent / 10percent aq. NaIO4, RuO2*H2O / ethyl acetate View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 10 p. 2715 - 2723
反应条件
1: 1.) O3, 2.) (CH3)2S / 1.) CH2Cl2, -78 deg C, 2.) -78 deg C to room temp. 2: 81 percent / 10percent aq. NaIO4, RuO2*H2O / ethyl acetate View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 10 p. 2715 - 2723
反应条件
1: HCR-W2 H+-Dowex resin / acetone 2: DMAP; Et3N / CH2Cl2 / 6 h / 0 °C 3: 4.00 g / KMnO4 / acetone / 6 h / 50 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 31 p. 6609 - 6617
反应条件
1: 63 percent / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature 2: 1.) O3, 2.) (CH3)2S / 1.) CH2Cl2, -78 deg C, 2.) -78 deg C to room temp. 3: 81 percent / 10percent aq. NaIO4, RuO2*H2O / ethyl acetate View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 10 p. 2715 - 2723
反应条件
1: boron trifluoride diethyl etherate / acetone / 20 °C / |Inert atmosphere 2: 1H-imidazole / N,N-dimethyl-formamide / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 12 p. 2293 - 2297
反应条件
1: HCR-W2 H+-Dowex resin / acetone / 4 h / 20 °C 2: 688 mg / DMAP; Et3N / CH2Cl2 / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 31 p. 6609 - 6617
反应条件
antimony(V) pentachloride; water in acetonitrile T=20°C; 0.166667 h;
参考文献
Gloria, Paulo M. C.; Prabhakar, Sundaresan; Lobo, Ana M.; Gomes, Mario J. S.
Tetrahedron Letters, 2003 , vol. 44, # 49 p. 8819 - 8821
