反应条件
1.1: n-BuLi / diethyl ether; hexane / 0.08 h / 0 °C
1.2: 62 percent / diethyl ether; hexane / 0.17 h / 0 °C
2.1: 83 percent / H2 / Pd/C / ethanol / 2.5 h
3.1: 89 percent / HCl / methanol / 7 h / 20 °C
4.1: 77 percent / K2CO3 / methanol / 0.33 h / 20 °C
5.1: 84 percent / NaBH4 / methanol / 0.5 h / 20 °C
View Scheme
参考文献
Arasaki, Hideki; Iwata, Masashi; Makida, Miyuki; Masaki, Yukio
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 7 p. 848 - 852
