(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯合成路线

755039-53-3(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯

755038-02-94-[[(7R)-8-环戊基-7-乙基-5,6,7,8-四氢-5-甲基-6-氧代-2-喋啶基]氨基]-3-甲氧基-N-(1-甲基-4-哌啶基)苯甲酰胺

参考文献

Budin, Ghyslain; Yang, Katherine S.; Reiner, Thomas; Weissleder, Ralph
Angewandte Chemie - International Edition, 2011 , vol. 50, # 40 p. 9378 - 9381

755039-52-2(2R)-2-(环戊氨基)-丁酸甲酯+

49845-33-22,4-二氯-5 硝基嘧啶

755039-53-3(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯

参考文献

SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD.
Patent: US2012/184543 A1, 2012 ;
Location in patent: Page/Page column 24 ;

755039-53-3(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯

参考文献

Boehringer Ingelheim International GmbH
Patent: US2006/35902 A1, 2006 ;
Location in patent: Page/Page column 5; 6 ;

74645-03-7

755039-53-3(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯

参考文献

ELAN PHARMACEUTICALS, INC.; GALEMMO, Robert, A., Jr.; ARTIS, Dean, Richard; YE, Xiaocong, Michael; AUBELE, Danielle, L.; TRUONG, Anh, P.; BOWERS, Simeon; HOM, Roy, K.; ZHU, Yong-Liang; NEITZ, R., Jeffrey; SEALY, Jennifer; ADLER, Marc; BEROZA, Paul; ANDERSON, John, P.
Patent: WO2011/79114 A1, 2011 ;
WO 2011/079114 A1

755039-53-3(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯

755039-54-4(7R)-2-氯-8-环戊烷基-7-乙基-7,8-二氢-6(5H)-蝶啶酮

参考文献

SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD.
Patent: US2012/184543 A1, 2012 ;
Location in patent: Page/Page column 24 ;

755039-53-3(2R)-2-[(2-氯-5-硝基-4-嘧啶基)环戊胺基]-丁酸甲酯

755039-56-6

参考文献

Budin, Ghyslain; Yang, Katherine S.; Reiner, Thomas; Weissleder, Ralph
Angewandte Chemie - International Edition, 2011 , vol. 50, # 40 p. 9378 - 9381