1-苄基-4-(3-氟苯基)-1,2,3,6-四氢吡啶合成路线 （共 3 条）
反应条件
hydrogenchloride in ethanol; water
50 h; Heating;
参考文献
Nagai, Yasutaka; Hino, Katsuhiko; Uno, Hitoshi; Minami, Shinsaku
Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 5 p. 1387 - 1393
反应条件
1: 1.) Mg / 1.) THF, reflux, 1 h 2.) THF, reflux, 20 h
2: conc. HCl / ethanol; H2O / 50 h / Heating
View Scheme
参考文献
Nagai, Yasutaka; Hino, Katsuhiko; Uno, Hitoshi; Minami, Shinsaku
Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 5 p. 1387 - 1393
反应条件
1: 1.) Mg / 1.) THF, reflux, 1 h 2.) THF, reflux, 20 h
2: conc. HCl / ethanol; H2O / 50 h / Heating
View Scheme
参考文献
Nagai, Yasutaka; Hino, Katsuhiko; Uno, Hitoshi; Minami, Shinsaku
Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 5 p. 1387 - 1393
