4-(3-硝基苯基)-2-甲醛基-6-甲基-1,4-二氢吡啶-3,5-二羧酸 5-异丙酯-3-甲酯合成路线 （共 7 条）
反应条件
hydrogenchloride in acetone 1 h; Ambient temperature;
参考文献
Satoh; Ichihashi; Okumura
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 12 p. 3189 - 3201
反应条件
1: 3 h / 100 - 120 °C 2: 6N HCl / acetone / 3 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 28 p. 5747 - 5754
反应条件
1: piperidine / benzene / 5 h / Heating 2: 3 h / 100 - 120 °C 3: 6N HCl / acetone / 3 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 28 p. 5747 - 5754
反应条件
1: 3 h / 100 - 120 °C 2: 6N HCl / acetone / 3 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 28 p. 5747 - 5754
反应条件
1: piperidine / benzene / 5 h / Heating 2: 3 h / 100 - 120 °C 3: 6N HCl / acetone / 3 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 28 p. 5747 - 5754
反应条件
1: 49 percent / propan-2-ol / 10 h / Heating 2: 91 percent / aq. HCl / acetone / 3 h / 20 °C View Scheme
参考文献
Monatshefte fur Chemie, , vol. 130, # 10 p. 1241 - 1252
反应条件
hydroxylamine hydrochloride; sodium acetate; acetic anhydride 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h; Yield given. Multistep reaction;
参考文献
Song, Yaoping; Shen, Dongguo; Zhang, Qinghua; Chen, Bo; Xu, Guangyu
Tetrahedron Letters, 2014 , vol. 55, # 3 p. 639 - 641
