反应条件
1: piperidine / benzene / 3 h / Heating 2: 51.1 percent / 8.5 h / 95 - 120 °C 3: 95.4 percent / 6 N aq. HCl / acetone / 1 h / Ambient temperature 4: 1.) NH2OH*HCl, NaOAc, 2.) Ac2O / 1.) AcOH, RT, 2.5 h, 2.) AcOH, a) RT, 1.5 h, b) 95 deg C - 100 deg C, 4 h View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 12 p. 3189 - 3201
