1: H2 / Pd-CaCO3 / methanol 2: H2 / Pd-CaCO3 / methanol 3: KHSO4 / 180 - 190 °C 4: H2 / Pd / methanol View Scheme

aluminum isopropoxide T=170 - 180°C;

triethylamine

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342937', constants.ctx, '0')">potassium hydroxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209237', constants.ctx, '0')">ethylene glycol dimethyl ether</a> <br />T=-10 - 0&deg;C;&nbsp;2.5&nbsp;h;&nbsp;<br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=0&deg;C;&nbsp;Grignard reaction;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587154', constants.ctx, '0')">ammonia</a> <br /> <br /> &nbsp;